article-type : Original Articles
Original Articles
Detection of SARS-CoV-2 from Patient Fecal Samples by Whole Genome Sequencing
Volume 2, No 1
Andreas Papoutsis, Thomas Borody, Siba Dolat, Jordan Daniels, Skylar Steinberg, Brad Barrows, Sabine Hazan
This study employs whole-genome sequencing to detect SARS-CoV-2 in fecal samples from COVID-19 patients, demonstrating 100% concordance with nasopharyngeal RT-PCR and highlighting the potential for fecal-oral transmission.
Original Articles
Impact of Acquired Hypernatremia in the ICU on Mortality in Patients with Acute Respiratory Failure: A Retrospective Analysis from the NIS Database
Volume 2, No 1
Edgar Selemi, Jose Iglesias, Matthew Halma, Joseph Varon
This original study uses data from the National Inpatient Sample to evaluate how ICU-acquired hypernatremia affects mortality and length of stay in patients with acute respiratory failure, identifying higher mortality and comorbidity-specific risks.
Original Articles
Metacritique of Influential Studies Purporting COVID-19 Vaccine Successes: Part 3
Volume 1, No 4
Raphael Lataster
In this third and final part of the metacritique, I evaluate four influential studies focused on Europe and Oceania: the European study by Meslé et al., Liu et al., and Lin et al. from Australia, and Datta et al. from New Zealand. These regional studies have significantly shaped public health messaging and vaccine policy. As in Parts 1 and 2, I identify recurring issues that call their conclusions into question — namely, problematic counting windows, inadequate accounting for adverse events, assumptions that exaggerate vaccine effectiveness, and potential conflicts of interest. Several studies also overlook waning or negative effectiveness and exclude safety signals, such as myocarditis. Collectively, these issues raise serious concerns about the reliability of models used to justify mass vaccination policies. A brief synthesis of all six studies is included to assess whether the prevailing narrative of universal COVID-19 vaccine benefit holds up under critical scrutiny.
Original Articles
Metacritique of Influential Studies Purporting COVID-19 Vaccine Successes: Part 2 – Kitano et al
Volume 1, No 3
Raphael Lataster
Continuing a series of metacritical analyses, this article dissects Kitano et al.’s modeling study claiming that mRNA COVID‑19 vaccines yield net benefits across all demographics. The author points out biased counting windows, exclusion of early adverse events, unfounded assumptions about safety and waning effectiveness, and conflicts of interest, arguing that such methodological flaws undermine the study’s conclusions.
Original Articles
COVID Skeptics Were Right: The US Government COVID-19 Report Vindicates Many Previously Contrarian Ideas
Volume 1, No 3
Raphael Lataster, Robert W. Malone
This editorial reviews the final report of the U.S. House Select Subcommittee on the Coronavirus Pandemic. It notes that the report validates numerous positions once labelled 'misinformation'—from lab‑leak origins and the failures of public health agencies to the ineffectiveness of mask mandates and lockdowns—and argues that incorporating dissenting perspectives will improve responses to future public health crises.
Original Articles
Low Rates of Hospitalization and Death in 4376 COVID-19 Patients Treated With Early Ambulatory Medical and Supportive Care: A Case Series and Observational Study
Volume 1, No 2
Brian M. Tyson, George Fareed, Emmanuel Beltran Gutierrez, Robert Villegas, Edgar Josue Anaya Gomez, Paloma Serrano Lopez, Ernesto Breton Herrera, Miriam Arlet Gutierrez Castro, Jesus Palomera III, Christiany Alexandrah Morales, Ana Mariella Escutia Gonzalez, Fabiola Tyson, Mathew Crawford
A large case series showing that early ambulatory multidrug treatment for COVID-19 drastically reduced hospitalization and death in 4376 patients in California.
Original Articles
Metacritique of Influential Studies Purporting COVID-19 Vaccine Successes: Part 1 - Watson et al
Volume 1, No 2
Raphael Lataster
A metacritique exposing major flaws in Watson et al’s claims that COVID-19 vaccines saved 14 million lives, challenging their data, assumptions, and conclusions.
Original Articles
Integrative Analysis of Neutrophil to Lymphocyte Ratio, CD4+, and CD8+ Cell Counts in COVID-19 Patients: A Retrospective Cohort Study
Volume 1, No 1
Claudia M. Ramirez, Mohamed Ziad-M. Said, Andreu Comas-Garcia, Pedro Carmo, Jesus Mendez-Castro, Joseph Varon
The study assessed outcomes in 985 COVID-19 patients, focusing on NLR, CD4+, and CD8+ cell counts. Patients with higher NLR or lower CD4+/CD8+ counts had increased mortality. Key findings include higher APACHE II, SOFA, and ICHIKADO scores, longer hospital stays, and a higher need for CPR in these groups.
