Journal of Independent Medicine
Current Issue
- Volume 1
- |
- No 3
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- August 12, 2025
Review Articles
Nucleoside-Modified RNA and Lipid Nanoparticles for "Therapeutic" Use – A Review for Lay People
Jessica Rose
This accessible review demystifies nucleoside‑modified RNA–lipid nanoparticle (modRNA–LNP) technology, the platform behind COVID‑19 vaccines. It explains how modRNA–LNPs deliver synthetic mRNA to cells, summarizes concerns about rushed clinical trials, waning effectiveness and adverse events, and discusses unanswered questions about long‑term safety and regulatory oversight.
Review Articles
COVID-19 mRNA-Induced "Turbo Cancers"
Paul Marik, Justus Hope
This review examines reports of unusually aggressive 'turbo cancers' emerging after mass COVID‑19 mRNA vaccination. Drawing on VAERS safety signals and mechanistic studies, the authors describe a multi‑hit hypothesis in which spike protein–mediated metabolic reprogramming, cancer stem‑cell propagation, apoptosis resistance and immune dysregulation may drive rapid tumor growth, and suggest that metabolic and repurposed therapies warrant further research.
Review Articles
Built Different: Functional Sleep Deprivation and the Elite Physician Phenotype
Joseph Varon
This narrative review explores whether some elite physicians can maintain high performance despite chronic sleep deprivation. Reviewing literature from sleep medicine, neuroscience and critical care, it identifies genetic and neuroplastic adaptations underlying a short‑sleep phenotype, but warns that sustained sleep loss still carries cognitive and physiological risks and urges healthcare systems to reevaluate cultures that normalize extreme endurance.
Review Articles
Pre-existing Immunity to COVID-19: Overview and Implications – Part 1
Rachel Nicoll
Part one of this three‑part review introduces evidence that prior exposure to common cold coronaviruses and other microbes can generate cross‑reactive T‑ and B‑cell responses against SARS‑CoV‑2. It discusses genetic similarities between human coronaviruses, early studies showing pre‑existing immunity in mucosal tissues, and how trained immunity and cross‑reactive antibodies may influence susceptibility, severity and vaccine design.
Review Articles
The Great PCR and HPAI Mistake
Roger S. Meacock
This review critiques the widespread use of polymerase chain reaction (PCR) tests as definitive diagnostics in veterinary medicine and in detecting highly pathogenic avian influenza (HPAI). The author explains that PCR amplifies genetic fragments but cannot determine infectivity, highlights false positives when cycles exceed a modest threshold, and warns that misinterpreting results leads to unnecessary culling and misguided disease policies.
Original Articles
Metacritique of Influential Studies Purporting COVID-19 Vaccine Successes: Part 2 – Kitano et al
Raphael Lataster
Continuing a series of metacritical analyses, this article dissects Kitano et al.’s modeling study claiming that mRNA COVID‑19 vaccines yield net benefits across all demographics. The author points out biased counting windows, exclusion of early adverse events, unfounded assumptions about safety and waning effectiveness, and conflicts of interest, arguing that such methodological flaws undermine the study’s conclusions.
Original Articles
COVID Skeptics Were Right: The US Government COVID-19 Report Vindicates Many Previously Contrarian Ideas
Raphael Lataster, Robert W. Malone
This editorial reviews the final report of the U.S. House Select Subcommittee on the Coronavirus Pandemic. It notes that the report validates numerous positions once labelled 'misinformation'—from lab‑leak origins and the failures of public health agencies to the ineffectiveness of mask mandates and lockdowns—and argues that incorporating dissenting perspectives will improve responses to future public health crises.
Medicolegal
A Health Declaration Grounded in Humanity, Science, and Wisdom: Reclaiming Health with the ACES Model
Jingduan Yang
This paper introduces the ACES Model—Anatomy, Chemistry, Energy and Soul—as a holistic framework for transforming healthcare. It argues that modern medicine excels at crisis management but often ignores whole‑person wellness, and calls for integrative, evidence‑informed reforms that address structural, biochemical, emotional and spiritual dimensions to prevent disease, restore health and empower patients and providers.
Letter to the Editor
Mortality Claims About Covid-19 Vaccinations
Paul Zarembka
In this letter to the editor, the author critiques claims that COVID‑19 vaccines increased all‑cause mortality. Using English public health data from the Delta variant period, he shows that mortality rates per 100 000 were lower among fully vaccinated older adults than among unvaccinated peers and urges skeptics to engage with these data before questioning vaccine efficacy.
Letter to the Editor
Multiple Sclerosis Remission Is Possible
Bob Sblendorio, Christina Kiening
This letter describes a patient’s experience achieving multiple sclerosis remission after adopting the Coimbra Protocol, a regimen of high‑dose vitamin D supervised by trained physicians. The authors explain the protocol’s requirements, discuss genetic polymorphisms affecting vitamin D metabolism, and encourage the Independent Medical Alliance to train clinicians so more patients can access this life‑changing therapy.
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